Development of resorbable nanocomposite tracheal and bronchial scaffolds for paediatric applications. BJS 2015; 102.
Published: 27th January 2015
Authors: G. Z. Teoh, C. Crowley, M. A. Birchall, A. M. Seifalian
Congenital tracheal defects and prolonged intubation following premature birth have resulted in an unmet clinical need for tracheal replacement. Advances in stem cell technology, tissue engineering and material sciences have inspired the development of a resorbable, nanocomposite tracheal and bronchial scaffold.
A bifurcated scaffold was designed and constructed using a novel, resorbable nanocomposite polymer, polyhedral oligomeric silsesquioxane poly(ϵ‐caprolactone) urea urethane (
This mechanically viable scaffold successfully supports
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