Functional mucous layer and healing of proximal colonic anastomoses in an experimental model. BJS 2017; 104: 619-630.
Published: 13th February 2017
Authors: J. W. A. M. Bosmans, A. C. H. M. Jongen, G. M. H. Birchenough, E. E. L. Nyström, M. J. J. Gijbels, J. P. M. Derikx et al.
Anastomotic leakage (
Mice of different Muc2 genotypes were used in a proximal colonic
Of 22 Muc2‐deficient (Muc2−/−) mice, 20 developed
A functional mucous layer facilitates the healing of colonic anastomoses. Colorectal anastomotic leakage remains the most dreaded complication after colorectal surgery. It is known that the aetiology of anastomotic leakage is multifactorial, and a role is suggested for the interaction between intraluminal content and mucosa.
Colorectal anastomotic leakage remains the most dreaded complication after colorectal surgery. It is known that the aetiology of anastomotic leakage is multifactorial, and a role is suggested for the interaction between intraluminal content and mucosa.Full text
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