Impact of early postoperative platelet count on volumetric liver gain and perioperative outcomes after major liver resection. BJS 2016; 103: 899-907.
Published: 9th March 2016
Authors: G. A. Margonis, N. Amini, S. Buettner, S. Besharati, Y. Kim, F. Sobhani et al.
Although perioperative platelet count has been associated with postoperative morbidity and mortality, its impact on liver regeneration has not been examined directly. This study sought to determine the impact of platelet count on liver regeneration after major liver resection using cross‐sectional imaging volumetric assessment.
Patients who underwent major liver resection between 2004 and 2015 and had available data on immediate postoperative platelet count, as well as preoperative and postoperative
A total of 99 patients met the inclusion criteria. Overall, 25 patients (25 per cent) had a low platelet count (less than 150 × 109/l), whereas 74 had a normal–high platelet count (at least 150 × 109/l). Despite having comparable clinicopathological characteristics and
After major liver resection, a low postoperative platelet count was associated with inhibited liver regeneration, as well as worse short‐ and long‐term outcomes. Immediate postoperative platelet count may be an early indicator to identify patients at increased risk of worse outcomes.Full text
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