Long‐term symptom control of gastro‐oesophageal reflux disease 12 years after laparoscopic Nissen or 180° anterior partial fundoplication in a randomized clinical trial.
Published: 3rd February 2017
Authors: D. J. Roks, J. A. Broeders, R. J. Baigrie
Laparoscopic 180° anterior fundoplication has been shown to achieve similar reflux control to Nissen fundoplication, with fewer side‐effects, up to 5 years. However, there is a paucity of long‐term follow‐up data on this technique and antireflux surgery in general. This study reports 12‐year outcomes of a double‐blind
Patients with proven
Of the initial 163 patients randomized (Nissen 84, anterior 79), 90 (55·2 per cent) completed 12‐year follow‐up (Nissen 52, anterior 38). There were no differences in heartburn, dysphagia, gas‐related symptoms, patient satisfaction or surgical reintervention rate. Use of acid‐suppressing drugs was less common after Nissen than after 180° anterior fundoplication: four of 52 (8 per cent) and 11 of 38 (29 per cent) respectively (
The two surgical procedures provided similar control of heartburn and post‐fundoplication symptoms, with similar patient satisfaction and reoperation rates on long‐term follow‐up.Read more
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