Meta‐analysis of an artery‐first approach versus standard pancreatoduodenectomy on perioperative outcomes and survival. BJS 2018; 105: 628-636.
Published: 13th April 2018
Authors: N. Ironside, S. G. Barreto, B. Loveday, S. V. Shrikhande, J. A. Windsor, S. Pandanaboyana et al.
The aim of this systematic review and meta‐analysis was to evaluate perioperative outcomes and survival in patients undergoing an artery‐first approach to pancreatoduodenectomy in comparison with those having standard pancreatoduodenectomy.
A systematic search of PubMed, MEDLINE, Embase and the Cochrane Database of Systematic Reviews was performed in accordance with PRISMA guidelines. Comparative studies including patients who underwent artery‐first pancreatoduodenectomy and standard pancreatoduodenectomy were analysed.
Seventeen studies were included in the final analysis. There were 16 retrospective cohort or case–control studies and one RCT. A total of 1472 patients were included in the meta‐analysis, of whom 771 underwent artery‐first pancreatoduodenectomy and 701 had standard pancreatoduodenectomy. Intraoperative blood loss (mean difference –389 ml;
The artery‐first approach to pancreatoduodenectomy may be associated with improved perioperative outcomes and survival.Full text
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