Multicentre observational study of adherence to Sepsis Six guidelines in emergency general surgery. BJS 2017; 104: e165-e171.
Published: 25th January 2017
Authors: N. S. Blencowe, S. Strong, J. Blazeby, R. Daniels, C. Peden, J. Lim et al.
Evidence‐based interventions may reduce mortality in surgical patients. This study documented the prevalence of sepsis, adherence to guidelines in its management, and timing of source control in general surgical patients presenting as an emergency.
Patients aged 16 years or more presenting with emergency general surgery problems were identified over a 7‐day period and then screened for sepsis compliance (using the Sepsis Six standards, devised for severe sepsis) and the timing of source control (whether radiological or surgical). Exploratory analyses examined associations between the mode (emergency department or general practitioner) and time of admission, adherence to the sepsis guidelines, and outcomes (complications or death within 30 days).
Of a total of 5067 patients from 97 hospitals across the
Although sepsis was common in general surgical patients presenting as an emergency, adherence to severe sepsis guidelines was incomplete in the majority. Despite this, no evidence of harm was apparent.Full text
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