Population‐based study of the sensitivity of axillary ultrasound imaging in the preoperative staging of node‐positive invasive lobular carcinoma of the breast. BJS 2018; 105: 987-995.
Published: 5th April 2018
Authors: E. Morrow, A. Lannigan, J. Doughty, J. Litherland, J. Mansell, S. Stallard et al.
Preoperative staging of the axilla is important to allow decisions regarding neoadjuvant treatment and the management of the axilla. Invasive lobular carcinoma metastases are difficult to detect because of the infiltrative pattern of the nodal spread. In this study the sensitivity of preoperative axillary staging between invasive lobular (ILC) and ductal (IDC) carcinoma was compared.
All women diagnosed with pure ILC or IDC in the West of Scotland in 2012–2014 were identified from a database maintained prospectively within the Managed Clinical Network. Pretreatment axillary ultrasound imaging (AUS), core biopsy and fine‐needle aspiration cytology (FNAC) results were compared between ILC and IDC.
Some 602 women with ILC and 4199 with IDC had undergone axillary surgery, of whom 209 and 1402 respectively had nodal metastases. Pretreatment AUS sensitivity was significantly lower in ILC than in IDC (32·1
AUS is inferior in detecting axillary node metastasis in ILC compared with IDC. Women with cT3–4 lobular carcinoma may benefit from ultrasound‐guided axillary biopsy regardless of the ultrasonographic appearance of the nodes.Full text
You may also be interested in
Randomized clinical trial
INTEND II randomized clinical trial of intraoperative duct endoscopy in pathological nipple discharge.
Authors: G. Gui, A. Agusti, D. Twelves, S. Tang, M. Kabir, C. Montgomery et al.
Notes: Identifies causative lesion
Aesthetic outcome following breast‐conserving surgery assessed by three evaluation modalities in relation to health‐related quality of life.
Authors: C. Dahlbäck, A. Ringberg, J. Manjer
Notes: Better methods needed
Current practice and short‐term outcomes of therapeutic mammaplasty in the international TeaM multicentre prospective cohort study.
Authors: R. L. O'Connell, E. Baker, A. Trickey, T. Rattay, L. Whisker, R. D. Macmillan et al.
Notes: Reduces mastectomy rates
Nationwide population‐based study of trends and regional variation in breast‐conserving treatment for breast cancer.
Authors: M. C. van Maaren, L. J. A. Strobbe, L. B. Koppert, P. M. P. Poortmans, S. Siesling
Notes: Regional differences remain
Survival and risk of breast cancer recurrence after breast reconstruction with deep inferior epigastric perforator flap. BJS 2018; 105: 1446-1453.
Authors: A. Svee, M. Mani, K. Sandquist, T. Audolfsson, Y. Folkvaljon, A. E. Isern et al.
Authors: N. Patani, F. MacAskill, S. Eshelby, A. Omar, A. Kaura, K. Contractor et al.
Notes: Outcomes improve
Meta‐analysis of the diagnostic accuracy of ultrasound‐guided fine‐needle aspiration and core needle biopsy in diagnosing axillary lymph node metastasis. BJS 2018; 105: 1244-1253.
Authors: I. Balasubramanian, C. A. Fleming, M. A. Corrigan, H. P. Redmond, M. J. Kerin, A. J. Lowery et al.
Notes: Core needle biopsy better
Meta‐analysis of the cumulative risk of endometrial malignancy and systematic review of endometrial surveillance in extended tamoxifen therapy. BJS 2018; 105: 1098-1106.
Authors: C. A. Fleming, H. M. Heneghan, D. O'Brien, D. P. McCartan, E. W. McDermott, R. S. Prichard et al.
Notes: Counselling of patients important
Breast‐conserving surgery followed by whole‐breast irradiation offers survival benefits over mastectomy without irradiation.
Authors: J. de Boniface, J. Frisell, L. Bergkvist, Y. Andersson
Notes: RT to lower axilla key?
Is axillary ultrasound imaging necessary for all patients with breast cancer?. BJS 2018; 105: 930-932.
Authors: M. Ahmed, M. Douek
Meta‐analysis of the oncological safety of autologous fat transfer after breast cancer. BJS 2018; 105: 1082-1097.
Authors: T. K. Krastev, S. J. Schop, J. Hommes, A. A. Piatkowski, E. M. Heuts, R. R. W. J. van der Hulst et al.
Notes: Lipofilling ok
Omission of surgery in older women with early breast cancer has an adverse impact on breast cancer‐specific survival. BJS 2018; 105: 1454-1463.
Authors: S. E. Ward, P. D. Richards, J. L. Morgan, G. R. Holmes, J. W. Broggio, K. Collins et al.
Notes: Surgery should be first choice