Synaptotagmin XIII expression and peritoneal metastasis in gastric cancer. BJS 2018; 105: 1349-1358.
Published: 9th May 2018
Authors: M. Kanda, D. Shimizu, H. Tanaka, C. Tanaka, D. Kobayashi, M. Hayashi et al.
Peritoneal metastasis is a frequent cause of death in patients with gastric cancer. The aim of this study was to identify molecules responsible for mediating peritoneal metastasis of gastric cancer.
Transcriptome and bioinformatics analyses were conducted to identify molecules associated with peritoneal metastasis. The therapeutic effects of intraperitoneally administered small interfering (si) RNA were evaluated using mouse xenograft models. Expression of mRNA and protein was determined in gastric tissues from patients with gastric cancer.
Synaptotagmin XIII (
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