Systematic review and meta‐analysis of the diagnostic accuracy of ductoscopy in patients with pathological nipple discharge. BJS 2016; 103: 632-643.
Published: 23rd March 2016
Authors: L. Waaijer, J. M. Simons, I. H. M. Borel Rinkes, P. J. van Diest, H. M. Verkooijen, A. J. Witkamp et al.
Invasive surgery remains the standard for diagnosis of pathological nipple discharge (
A systematic search of electronic databases for studies addressing ductoscopy in patients with
The search yielded 4642 original citations, of which 20 studies were included in the review. Malignancy rates varied from 0 to 27 per cent. Twelve studies, including 1994 patients, were eligible for meta‐analysis. Pooled sensitivity and specificity of
Ductoscopy detects about 94 per cent of all underlying malignancies in patients with PND, but does not permit reliable discrimination between malignant and benign findings.Full text
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