Systematic review of pressurized intraperitoneal aerosol chemotherapy for the treatment of advanced peritoneal carcinomatosis. BJS 2017; 104: 669-678.
Published: 13th April 2017
Authors: F. Grass, A. Vuagniaux, H. Teixeira‐Farinha, K. Lehmann, N. Demartines, M. Hübner et al.
Pressurized intraperitoneal aerosol chemotherapy (
This was a systematic review of the literature on pressurized intraperitoneal chemotherapy published between January 2000 and October 2016. All types of scientific report were included.
Twenty‐nine relevant papers were identified; 16 were preclinical studies and 13 were clinical reports. The overall quality of the clinical studies was modest; five studies were prospective and there was no randomized trial. Preclinical data suggested better distribution and higher tissue concentrations of chemotherapy agents in
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