Validation of two prognostic models for recurrence and survival after radical gastrectomy for gastric cancer.
Published: 10th May 2017
Authors: M. Bencivenga, G. Verlato, D.‐S. Han, D. Marrelli, F. Roviello, H.‐K. Yang et al.
Prognostic models from Korea and Italy have been developed that predict overall survival and cancer recurrence respectively after radical gastrectomy for gastric cancer. The aim of this study was to validate the two models in independent patient cohorts, and to evaluate which factors may explain differences in prognosis between Korean and Italian patients with gastric cancer.
Patients who underwent radical gastrectomy for gastric cancer between January 2000 and December 2004 at Seoul National University Hospital and at eight centres in Italy were included. Discrimination of the models was tested with receiver operating characteristic (
Some 2867 and 940 patients from Korea and Italy respectively were included. The Korean nomogram achieved good discrimination in the Italian cohort (
Both prognostic models performed fairly well in independent patient cohorts. Differences in recurrence rates of gastric cancer may be partially explained by ethnicity.Read more
You may also be interested in
Corrigendum: Metabolic nodal response as a prognostic marker after neoadjuvant therapy for oesophageal cancer. BJS 2017; 104: 947-947.
Authors: J. M. Findlay, K. M. Bradley, L. M. Wang, J. M. Franklin, E. J. Teoh, F. V. Gleeson et al.
Preoperative imaging and prediction of oesophageal conduit necrosis after oesophagectomy for cancer.
Authors: P. Lainas, D. Fuks, S. Gaujoux, Z. Machroub, A. Fregeville, T. Perniceni et al.
Notes: Vascular abnormalities may be causal
Survival benefit of liver resection for Barcelona Clinic Liver Cancer stage B hepatocellular carcinoma. BJS 2017; 104: 1045-1052.
Authors: H. Kim, S. W. Ahn, S. K. Hong, K. C. Yoon, H.‐S. Kim, Y. R. Choi et al.
Notes: Selected patients benefit
Authors: Z.‐X. Wang, G.‐X. Li, Z.‐W. Zhou, Z.‐P. Huang, F. Wang, R.‐H. Xu et al.
Notes: Facilitates individualized treatment
Randomized clinical trial
Randomized clinical trial of landiolol hydrochloride for the prevention of atrial fibrillation and postoperative complications after oesophagectomy for cancer. BJS 2017; 104: 1003-1009.
Authors: T. Ojima, M. Nakamori, M. Nakamura, M. Katsuda, K. Hayata, T. Kato et al.
Notes: Prevention of atrial fibrillation is beneficial
Geographic and socioeconomic factors affecting delivery of bariatric surgery across high‐ and low‐utilization healthcare systems. BJS 2017; 104: 891-897.
Authors: A. G. Doumouras, F. Saleh, A. M. Sharma, S. Anvari, S. Gmora, M. Anvari et al.
Notes: Differences between rural and urban areas
Meta‐analysis of biomarkers predicting risk of malignant progression in Barrett’s oesophagus. BJS 2017; 104: 493-502.
Authors: K. Altaf, J.‐J. Xiong, D. De la Iglesia, L. Hickey, A. Kaul
Notes: Limited clinical usefulness at present
Randomized clinical trial
Randomized clinical trial of 270° posterior versus 180° anterior partial laparoscopic fundoplication for gastro‐oesophageal reflux disease. BJS 2017; 104: 843-851.
Authors: D. J. Roks, J. H. Koetje, J. E. Oor, J. A. Broeders, V. B. Nieuwenhuijs, E. J. Hazebroek et al.
Notes: No major differences in outcomes
Locoregional relapse after gastrectomy with D2 lymphadenectomy for gastric cancer. BJS 2017; 104: 877-884.
Authors: J. S. Chang, K. H. Kim, H. I. Yoon, W. J. Hyung, S. Y. Rha, H. S. Kim et al.
Notes: Can be predicted
Outcomes of laparoscopic gastric bypass in a randomized clinical trial compared with a concurrent national database. BJS 2017; 104: 562-569.
Authors: E. Stenberg, E. Szabo, J. Ottosson, I. Näslund
Notes: Similar results demonstrating external validity
Authors: L. A. D. Busweiler, M. G. Schouwenburg, M. I. van Berge Henegouwen, N. E. Kolfschoten, P. C. de Jong, T. Rozema et al.
Notes: Novel approach to quality assessment
Prognostic factors for survival in patients with pT1 N+ or T2–3 N0 gastric cancer in Japan. BJS 2017; 104: 885-890.
Authors: M. Tokunaga, S. Ito, T. Yoshikawa, S. Nunobe, T. Fukagawa, K. Misawa et al.
Notes: Low recurrence and excellent survival