A four-probiotics regimen reduces postoperative complications after colorectal surgery: a randomized, double-blind, placebo-controlled study. World J Surg 2015; 39: 2776-2783.

Published: 8th March 2016

Authors: Kotzampassi K, Stavrou G, Damoraki G, Georgitsi M, Basdanis G, Tsaousi G et al. et al.

Conclusion

This trial of perioperative probiotics was stopped early due to the significant reduction in postoperative complications (28.6 versus 48.8 per cent, P=0.01), surgical site infection (7.1 versus 20.0 per cent, P=0.02) and anastomotic leak (1.2 versus 8.8 per cent, P=0.03).

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