Antibiotic therapy for prevention of fistula in-ano after incision and drainage of simple perianal abscess: a randomized single blind clinical trial. Surgery 2017; 162: 1017-1025.

Published: 17th May 2018

Authors: Ghahramani L, Minaie MR, Arasteh P, Hosseini SV, Izadpanah A, Bananzadeh AM et al.


This study included 300 evaluable patients randomized to a one week course of postoperative metronidazole and ciprofloxacin or no antibiotic. The antibiotics reduced the rate of subsequent fistula at three months, P<0.001.

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