Antibiotics versus surgical therapy for uncomplicated appendicitis: systematic review and meta-analysis of controlled trials (PROSPERO 2015: CRD42015016882). Ann Surg 2017; 265: 889-900.

Published: 14th June 2017

Authors: Harnoss J, Zelienka I, Probst P, Grummich K, Müller-Lantzsch C, Harnoss J et al.


Four RCTs and four cohort studies were included (2551 patients). Some 26.5 per cent of patients treated conservatively needed appendicectomy within a year. Adverse events and duration of hospital stay were longer in the antibiotic group.

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