Autologous myoblasts for the treatment of fecal incontinence; results of a phase 2 randomized placebo-controlled study (MIAS). Ann Surg 2018; 267: 443–450.

Published: 17th May 2018

Authors: Boyer O, Bridoux V, Giverne C, Bisson A, Koning E, Leroi A-M et al.


Intrasphincteric injection of myoblasts was safe and well tolerated, and improved faecal incontinence scores at 12 months (but not six months) in this study of 24 patients: score 6.5 versus 15, P=0.006.

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