Clinical effectiveness of neoadjuvant chemotherapy in advanced gastric cancer: an updated meta-analysis of randomized controlled trials. Eur J Surg Oncol 2014; 40: 1321-1330.

Published: 24th February 2015

Authors: Xiong B, Ma L, Cheng Y, Zhang C


This study examined 12 trials of 1820 patients. Neoadjuvant chemotherapy did not increase perioperative morbidity or mortality, but it did improve 3-year progression-free survival: odds ratio 1.85, 95 per cent confidence interval 1.39 to 2.46, P<0.0001.

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