Clopidogrel plus aspirin versus aspirin alone for acute minor ischaemic stroke or high-risk transient ischaemic attack. BMJ 2018; 363: k5108.

Published: 9th April 2019

Authors: Hao Q, Tampi M, O’Donnell M, Foroutan F, Siemieniuk RAC, Guyatt G et al.


Some 10447 patients were included. Dual antiplatelets reduced the risk of non-fatal recurrent stroke (relative risk 0.70, 95 per cent confidence interval 0.61 to 0.8, absolute risk reduction 1.9 per cent. They did not affect all-cause mortality.

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