Crohn’s disease management after intestinal resection: a randomised trial. Lancet 2015; 385:1406–1417.

Published: 23rd June 2015

Authors: De Cruz P, Kamm MA, Hamilton AL, Ritchie KJ, Krejany EO, Gorelik A et al. et al.


Patients were included if they had an anastomosis accessible to colonoscopy and all received 3 months of metronidazole postoperatively. Some 174 patients were randomly assigned colonoscopic or standard follow-up, with stepped-up care for local recurrence. After 18 months, endoscopic recurrence occurred in 49 per cent of patients having active care versus 67 per cent having standard care (P=0.03).

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