Effect of cephalexin plus trimethoprim-sulfamethoxazole vs cephalexin alone on clinical cure of uncomplicated cellulitis. A randomized clinical trial. JAMA. 2017; 317: 2088-2096.

Published: 14th June 2017

Authors: Moran GJ, Krishnadasan A, Mower WR, Abrahamian FM, LoVecchio F, Steele MT et al.


The addition of trimethoprim-sulfamethoxazole did not improve the clinical cure rate (83.5 per cent versus 85.5 per cent with cehpalexin alone) in this study that included 500 patients.

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