Effect of fish oil supplementation on graft patency and cardiovascular events among patients with new synthetic arteriovenous hemodialysis grafts. A randomized controlled trial. JAMA 2012; 307: 1809–1816.

Published: 12th November 2012

Authors: Lok CE, Moist L, Hemmelgam BR, Tonelli M, Vazquez MA, Dorval M et al.


Fish oil did not affect the composite primary endpoint of ‘graft thrombosis or radiological or surgical intervention over twelve months’ in this study that included 196 patients: relative risk 0.78, 95 per cent confidence interval 0.6 to 1.03, P=0.06. It did reduce the rate of dialysis graft failure: 0.58, 0.44 to 0.75, P<0.001.

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