Effect of oral capsule vs. colonoscopy-delivered fecal microbiota transplantation on recurrent Clostridium difficile infection. A randomized clinical trial JAMA 2017; 318: 1985-1993.

Published: 22nd February 2018

Authors: Kao D, Roach B, Silva M, Beck P, Rioux K, Kaplan GG et al.


Some 116 patients each received a single treatment. The risk of recurrent C diff was similar after 12 weeks: 2/53 after capsule and 2/52 after colonoscopy. Quality-of-life rates were also similar. Patients found the capsule method less unpleasant, P=0.01.

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