Effect of a scalp cooling device on alopecia in women undergoing chemotherapy for breast cancer. The SCALP randomized clinical trial. JAMA 2017; 317: 596-605.

Published: 30th March 2017

Authors: Nangia J, Wang T, Osborne C, Niravath P, Otte K, Papish S et al.


The trial was stopped early after 142 women had been randomized. The trial endpoint (<50 per cent hair loss, not needing a wig) was reached by 50.5 per cent of cooled women, compared to none in the control group, P=0.0061.

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