Efficacy of a single preoperative dexamethasone dose to prevent nausea and vomiting after thyroidectomy (the tPONV Study): a randomized, double-blind, placebo-controlled clinical trial. Ann Surg 2015; 262: 934-940.

Published: 8th March 2016

Authors: Tarantino I, Warschkow R, Beutner U, Kolb W, Lüthi A, Lüthi C et al. et al.


Dexamethasone reduced postoperative nausea and vomiting: odds ratio 0.31, 95 per cent confidence interval 0.16 to 0.61, absolute risk reduction 28 per cent; P=0.001. Number needed to treat was four. There were no major adverse events in this study that included 152 patients.

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