Efficacy of preoperative oral antibiotic prophylaxis for the prevention of surgical site infections in patients with Crohn’s Disease. A Randomized Controlled Trial. Ann Surg 2019; 269: 420-426.

Published: 21st June 2019

Authors: Uchino M, Ikeuchi H, Bando T, Chohno T, Sasaki H, Horio Y et al.


The addition of oral antibiotics to intravenous antibiotic prophylaxis reduced the rate of surgical site infection from 27/162 (16.6 per cent) to 12/163 (7.4 per cent), P=0.01.

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