Extended antibiotic therapy versus placebo after laparoscopic cholecystectomy for mild and moderate acute calculous cholecystitis: A randomized double-blind clinical trial. Surgery 2018; 164: 24-30.

Published: 22nd November 2018

Authors: de Santibañes M, Glinka J, Pelegrini P, Alvarez FA, Elizondo C, Giunta D et al.


An additional five days of antibiotics did not reduce the rate of infective complications (5.8 per cent versus 6.6 per cent with placebo) in this trial that included 195 procedures.

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