Fibrin sealant with polyglycolic acid felt vs fibrinogen-based collagen fleece at the liver cut surface for prevention of postoperative bile leakage and hemorrhage: a prospective, randomized, controlled study. J Am Coll Surg 2016; 222: 59-64.

Published: 28th September 2016

Authors: Kobayashi S, Takeda Y, Nakahira S, Tsujie M, Shimizu J, Miyamoto A et al.


The rates of postoperative bile leak (4.1 per cent with fibrin sealant vs. 5.1 per cent with collagen fleece) and haemorrhage (1 per cent in both groups) were similar in this trial that included 391 procedures.

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