Frozen vs fresh fecal microbiota transplantation and clinical resolution of diarrhea in patients with recurrent Clostridium difficile infection. A randomized clinical trial. JAMA 2016; 315: 142-149.

Published: 29th February 2016

Authors: Lee CH, Steiner T, Petrof EO, Smieja M, Roscoe D, Nematallah A et al. et al.


Some 219 patients were randomized to receive fresh or (thawed) frozen bacteria. Both were equally effective at achieving clinical resolution: per protocol results 85.1 per cent fresh versus 83.5 per cent frozen.

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