Gemcitabine alone versus gemcitabine plus radiotherapy in patients with locally advanced pancreatic cancer: an Eastern Cooperative Oncology Group trial. J Clin Oncol 2011; 29: 4105–4112.

Published: 30th April 2012

Authors: Loehrer Sr PJ, Feng Y, Cardenes H, Wagner L, Brell JM, Cella D et al.


The addition of radiotherapy to chemotherapy was studied in 74 patients with an inoperable tumour. The radiotherapy group had prolonged survival (11.1 versus 9.2 months, P=0.017), but at the expense of more toxicity.

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