Laparoscopic cholecystectomy versus percutaneous catheter drainage for acute cholecystitis in high risk patients (CHOCOLATE): multicentre randomised clinical trial. BMJ 2018; 363: k3965.

Published: 6th February 2019

Authors: Loozen CS, van Santvoort HC, van Duijvendijk P, Besselink MG, Gouma DJ, Nieuwenhuijzen GA et al.


Some 134 high risk patients with acute cholecystitis were included. One year survival rates were similar, but major complications were much more frequent in the drainage group: 65 versus 12 per cent, P<0.001.

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