Ligation of intersphincteric fistula tract vs ligation of the intersphincteric fistula tract plus a bioprosthetic anal fistula plug procedure in patients with transsphincteric anal fistula: early results of a multicenter prospective randomized trial. Ann Surg 2016; 264: 917-922.

Published: 2nd February 2017

Authors: Han JG, Wang ZJ, Zheng Y, Chen CW, Wang XQ, Che XM et al.


The addition of the fistula plug improved early healing rates (median 22 versus 30 days, P<0.001). It did not affect postoperative pain scores, which were similar, in this multicentre study that included 235 patients.

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