Local treatment of unresectable colorectal liver metastases: results of a randomized phase II trial. J Natl Cancer Inst 2017; 109. doi: 10.1093/jnci/djx015.

Published: 5th January 2018

Authors: Ruers T, Van Coevorden F, Punt CJA, Pierie J-PEN, Borel-Rinkes I, Ledermann JA et al.


Some 119 patients with irresectable liver metastasis were offered chemotherapy with, or without radio frequency ablation. After a median of 9.7 years, patients who had radiofrequency had improved overall survival: hazard ratio 0.58, 95 per cent confidence interval 0.38 to 0.88, P=0.01.

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