Low ligation of inferior mesenteric artery in laparoscopic anterior resection for rectal cancer reduces genitourinary dysfunction. Results from a randomized controlled trial (HIGHLOW Trial). Ann Surg 2019; 269: 1018-1024.

Published: 2nd September 2019

Authors: Mari G, Crippa J, Cocozza E, Berselli M, Livraghi L, Carzaniga P et al.


There were no differences in perioperative outcomes and initial oncological outcomes in this study that included 214 patients. Patients who had low mesenteric ligation had improved quality of life after 9 months, better continence and fewer obstructive urological symptoms.

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