Open-label, multicentre, randomized phase III trial of adjuvant chemoradiation plus interferon alfa-2b versus fluorouracil and folinic acid for patients with resected pancreatic adenocarcinoma. J Clin Oncol 2012; 30: 4077–4083.

Published: 4th March 2013

Authors: Schmidt J, Abel U, Debus J, Harig S, Hoffman K, Herrmann T et al. et al.


The addition of postoperative radiotherapy and interferon did not improve overall median survival in this trial that included 132 patients: 26.5 months versus 28.5 months after standard chemotherapy (P=0.99).

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