Perioperative chemotherapy compared with surgery alone for resectable gastroesophageal adenocarcinoma: an FNCLCC and FFCD multicenter phase III Trial. J Clin Oncol 2011; 29: 1715–1721.

Published: 7th July 2011

Authors: Ychou M, Boige V, Pignon J-P, Conroy T, Bouche O, Lebreton G et al. et al.


Some 224 patients were included in the study. Chemotherapy improved five year disease-free survival from 19 to 34 per cent: hazard ratio 0.65, 95 per cent confidence interval 0.48 to 0.89, P=0.003; and overall survival from 24 to 38 per cent (0.69, 0.5 to 0.95, P=0.02).

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