Perioperative single dose ketorolac to prevent postoperative pain: a meta-analysis of randomized trials. Anesth Analg 2012; 114: 424-433.

Published: 4th April 2012

Authors: De Oliveira GS Jr, Agarwal D, Benzon HT


The analysis included 13 trials with 782 patients. 60mg ketorolac significantly reduced early postoperative pain at rest (weighted mean difference -0.64, 95 per cent confidence interval -1.11 to -0.18), and opioid consumption. It did not affect late pain.

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