Pioglitazone after ischemic stroke or transient ischemic attack. N Engl J Med 2016; 374: 1321-1331.

Published: 15th June 2016

Authors: Kernan WN, Viscoli CM, Furie KM, Young LH, Inzucchi SE, Gorman M et al.

Conclusion

Some 3876 patients with insulin resistance, but not frankly diabetic, were included. Pioglitazone 45m daily reduced the risk of subsequent stroke or myocardial infarction up to a median 4.8 years from 11.8 per cent with placebo to 9 per cent, P=0.007.

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