Prophylactic hydration to protect renal function from intravascular iodinated contrast material in patients at high risk of contrast-induced nephropathy (AMACING): a prospective, randomised, phase 3, controlled, open-label, non-inferiority trial. Lancet 2017; 389: 1312–1322.

Published: 17th May 2017

Authors: Nijssen EC, Rennenberg RJ , Nelemans PJ, Essers BA, Janssen MM, Vermeeren MA et al.


Some 660 procedures were included in patients with eGFR from 30-59ml/min. Contrast-induced nephropathy rates were similar in hydrated (2.7 per cent) and non-hydrated patients (2.6 per cent).

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