Prospective randomized controlled trial of liberal vs. restricted perioperative fluid management in patients undergoing pancreatectomy. Ann Surg 2016; 264: 591-598.

Published: 9th November 2016

Authors: Grant F, Brennan MF, Allen PJ,, DeMatteo RP, Kingham TP, D’Angelica M et al.


A total of 330 patients were randomized. There were two deaths. Postoperative complication rates were similar after liberal (20 per cent) and restricted (27 per cent) regimens, P=0.6.

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