Prospective, randomized, mulitcenter, controlled trial of a bioartificial liver in treating acute liver failure. Ann Surg 2004; 239: 660-670.

Published: 1st January 2004

Authors: Demetriou AA, Brown RS Jr, Busuttil RW, Fair J, McGuire B, Rosenthal P et al.


In a study that included 171 patients with fulminant liver failure, survival after 30 days was similar if the artificial liver was used. If confounding factors were accounted for and the analysis confined to those who had not had a transplant, survival was improved with the artificial liver (risk ratio 0.56, p=0.48).

Pubmed Link

Your comments