Protection of pharmacological postconditioning in liver surgery: results of a prospective randomized controlled trial. Ann Surg 2012; 256: 837–845.

Published: 4th March 2013

Authors: Beck-Schimmer B, Breitenstein S, Bonvini JM, Lesurtel M, Ganter M, Weber A et al. et al.


There were three arms in this study that included 115 procedures: intermittent inflow clamping, sevoflurane (pharmacological postconditioning) and continuous inflow occlusion (control). Both active interventions improved postoperative liver function, reduced complications and shortened hospital stay by 2-4 days.

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