Randomized, double-blind, controlled trial of early endoscopic ultrasound-guided celiac plexus neurolysis to prevent pain progression in patients with newly diagnosed, painful, inoperable pancreatic cancer. J Clin Oncol 2011; 29: 3541–3546.

Published: 21st February 2012

Authors: Wyse JM, Carone M, Paquin SC, Usatill M, Sahai AV


Ninety-six patients were included. There was no effect on quality of life or survival. Coeliac plexus block significantly reduced pain scores after one (P=0.09) and three months (P=0.01), and tended to reduce the need for morphine consumption at three months.

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