Somatostatin analogues for the treatment of enterocutaneous fistulas: a systematic review and meta-analysis. World J Surg 2012; 36: 1016-1029.

Published: 11th February 2013

Authors: Coughlin S, Roth L, Lurati G, Faulhaber M


Eight randomized trials were analyzed. Somatostatin had no effect on mortality, but it did reduce the time to closure of the fistula (weighted mean difference -6.37 days, 95 per cent confidence interval -8.83 to -4.42) and the duration of hospital stay (-4.53 days, -8,29 to -0.77).

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