Surgery alone versus chemoradiotherapy followed by surgery for stage I and II esophageal cancer: final analysis of randomized controlled phase III trial FFCD 9901. J Clin Oncol 2014; 32: 2416-2422.
Published: 5th February 2015
Authors: Mariette C, Dahan L, Mornex F, Maillard E, Thomas P-A, Meunier B et al. et al.
In this trial that included 195 patients followed for a median of 94 months, three-year survival after chemoradiotherapy (47.5 per cent) was similar to that after surgery alone (53 per cent). The trial was stopped for futility.Pubmed Link
You may also be interested in
Pouch versus no pouch following total gastrectomy: meta-analysis of randomized and non-randomized studies. Ann Surg 2019; 269: 1041-1053.
Authors: Syn N, Wee I, Shabbir A, Kim G, So JB-Y
Risk of appendiceal neoplasm in periappendicular abscess in patients treated with interval appendectomy vs follow-up with magnetic resonance imaging. 1-year outcomes of the Peri–appendicitis Acuta randomized clinical trial. JAMA Surg 2019; 154: 200-207.
Authors: Mällinen J, Rautio T, Grönroos J, Rantanen T, Nordström P, Savolainen H et al.
Effect of laparoscopic vs open distal gastrectomy on 3-year disease-free survival in patients with locally advanced gastric cancer. The CLASS-01 randomized clinical trial. JAMA 2019; 321: 1983-1992.
Authors: Yu J, Huang C, Sun Y, Su X, Cao H, Hu J et al.
A randomized double blinded study to determine the effectiveness of utilizing intraperitoneal bupivacaine: does it reduce postoperative opioid use following laparoscopic appendectomy? Am J Surg 2019; 217: 479-482.
Authors: Sevensma K, Schleichert T, Shwickerath C, Shoemaker A, Miller C
Efficacy of transversus abdominis plane (TAP) block in pain management after laparoscopic sleeve gastrectomy (LSG): A double-blind randomized controlled trial. Am J Surg 2019; 217: 126-132.
Authors: Saber AA, Lee YC, Arjun C, Namik O, Armand A, Al-Ayoubi S et al.
Perioperative chemotherapy with fluorouracil plus leucovorin, oxaliplatin, and docetaxel versus fluorouracil or capecitabine plus cisplatin and epirubicin for locally advanced, resectable gastric or gastro-oesophageal junction adenocarcinoma (FLOT4): a randomised, phase 2/3 trial. Lancet 2019; 393: 1948-1957.
Authors: Al-Batran S-E, Homann N, Pauligk C, Goetze TO, Meiler J, Kasper S et al.
Robot-assisted minimally invasive thoracolaparoscopic esophagectomy versus open transthoracic esophagectomy for resectable esophageal cancer. A randomized controlled trial. Ann Surg 2019; 269: 621-630.
Authors: van der Sluis PC, van der Horst S, May AM, Schippers C, Brosens L, Joore HC et al.
Efficacy of preoperative oral antibiotic prophylaxis for the prevention of surgical site infections in patients with Crohn’s Disease. A Randomized Controlled Trial. Ann Surg 2019; 269: 420-426.
Authors: Uchino M, Ikeuchi H, Bando T, Chohno T, Sasaki H, Horio Y et al.
Efficacy and safety of one anastomosis gastric bypass versus Roux-en-Y gastric bypass for obesity (YOMEGA): a multicentre, randomised, open-label, non-inferiority trial. Lancet 2019; 393: 1299-1309.
Authors: Maud R, Espalieu P, Pelascini E, Caiazzo R, Sterkers A, Khamphommala L et al.
Effect of perioperative oral nutritional supplementation in malnourished patients who undergo gastrectomy: a prospective randomized trial. Surgery 2018; 164: 1263-1270.
Authors: Kong S-H, Lee H-J, Na J-R, Kim WG, Han D-S, Park S-H et al.
Effect of exercise and nutrition prehabilitation on functional capacity in esophagogastric cancer surgery. A randomized clinical trial. JAMA Surg 2018; 153: 1081-1089.
Authors: Minnella EM, Awasthi R, Loiselle S-E, Agnihotram RV, Ferri LE, Carli F et al.
Authors: Mariette C, Markar SR, Dabakuyo-Yonli TS, Meunier B, Pezet D, Collet D et al.