The effect of intraoperative nefopam administration on acute postoperative pain and chronic discomfort after robotic or endoscopic assisted thyroidectomy: a randomized clinical Trial. World J Surg 2018; 42: 2094-2101.

Published: 27th February 2019

Authors: Kim BG, Moon JY, Choi JY, Park IS, Oh AY, Jeon YT et al.


In this study of 58 procedures, the nefopam infusion reduced postoperative pain scores up to 48h (P<0.05), and fewer patients needed rescue analgesia (P=0.001).

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