Topical minoxidil versus topical diltiazem for chemical sphincterotomy of chronic anal fissure: a prospective, randomized, double-blind, clinical trial. World J Surg 2018; 42: 2252–2258.

Published: 27th February 2019

Authors: Alvandipour M, Ala S, Khalvati M, Yazdanicharati J, Koulaeinejad N


In this study that included 88 patients, there was no difference between minoxidil and diltiazem in healing rates after two months, or symptoms during healing.

Pubmed Link

Your comments